Product Data Sheet
CT-996
Catalog No. A59080
CT-996 is an orally active GLP-1 receptor (GLP-1R) agonist with an EC50 of 0.49 nM, modulating glucose metabolism through its effects on β-arrestin recruitment and receptor internalization. This compound significantly lowers postprandial blood glucose levels in mice engineered to express human GLP-1 receptors and enhances glucose-stimulated insulin secretion (GSIS) in obese monkey models during intravenous glucose challenges. CT-996 serves as a valuable tool for research focused on type 2 diabetes and obesity.
Chemical Information
| Catalog Num | A59080 |
|---|---|
| M. Wt | 579.59 |
| Formula | C30H31F2N5O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2810808-95-6 |
| Synonyms | RO7795081; RG6652 |
| SMILES | C[C@@H](C[C@H](CC1)OC2=NC(COC3=C(C=C(C=C3)F)F)=NC=C2)N1CC(N(C4=C5)C[C@@H]6CCO6)=NC4=CC=C5C(O)=O |
Biological Activity
| Description | CT-996 is an orally active GLP-1 receptor (GLP-1R) agonist with an EC50 of 0.49 nM, modulating glucose metabolism through its effects on β-arrestin recruitment and receptor internalization. This compound significantly lowers postprandial blood glucose levels in mice engineered to express human GLP-1 receptors and enhances glucose-stimulated insulin secretion (GSIS) in obese monkey models during intravenous glucose challenges. CT-996 serves as a valuable tool for research focused on type 2 diabetes and obesity. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
