Product Data Sheet
AM-6538
Catalog No. A59192
AM-6538 is a high-affinity, pseudo-irreversible cannabinoid (CB) antagonist that serves as a valuable tool for research on cannabinoid receptor modulation. As a structural analog of rimonabant, it effectively evaluates the efficacy of both full and partial agonists at cannabinoid receptors. Additionally, AM-6538's unique alkyne group allows it to function as a click chemistry reagent, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. This makes it suitable for applications that require temporary modulation of cannabinoid receptor availability.
Chemical Information
| Catalog Num | A59192 |
|---|---|
| M. Wt | 542.41 |
| Formula | C26H25Cl2N5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1245626-00-9 |
| Synonyms | |
| SMILES | O=C(C1=NN(C2=CC=C(Cl)C=C2Cl)C(C3=CC=C(C#CCCO[N+]([O-])=O)C=C3)=C1C)NN4CCCCC4 |
Biological Activity
| Description | AM-6538 is a high-affinity, pseudo-irreversible cannabinoid (CB) antagonist that serves as a valuable tool for research on cannabinoid receptor modulation. As a structural analog of rimonabant, it effectively evaluates the efficacy of both full and partial agonists at cannabinoid receptors. Additionally, AM-6538's unique alkyne group allows it to function as a click chemistry reagent, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. This makes it suitable for applications that require temporary modulation of cannabinoid receptor availability. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
