Product Data Sheet

GW 833972A

Catalog No. A59195

main product photo
GW 833972A is a selective agonist of the CB2 receptor, exhibiting a pEC50 value of 7.3 for human CB2. With approximately 1000-fold higher selectivity for the CB2 receptor over CB1, GW 833972A effectively inhibits induced neuronal depolarization and alleviates cough reflex in guinea pig models. This compound is valuable for research into chronic cough mechanisms and potential therapeutic interventions.
Chemical Information
Catalog NumA59195
M. Wt444.24
FormulaC18H14Cl2F3N5O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1092502-33-4
Synonyms
SMILESO=C(C1=CN=C(NC2=CC=CC(Cl)=C2)N=C1C(F)(F)F)NCC3=CC=NC=C3.[H]Cl
Biological Activity
DescriptionGW 833972A is a selective agonist of the CB2 receptor, exhibiting a pEC50 value of 7.3 for human CB2. With approximately 1000-fold higher selectivity for the CB2 receptor over CB1, GW 833972A effectively inhibits induced neuronal depolarization and alleviates cough reflex in guinea pig models. This compound is valuable for research into chronic cough mechanisms and potential therapeutic interventions.
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