Product Data Sheet
Drinabant
Catalog No. A59201
Drinabant is a potent antagonist of the CB1 receptor, specifically designed for oral activity. It effectively inhibits agonist-stimulated calcium signaling, demonstrating IC50 values of 25 nM for human CB1 receptors and 10 nM for rat CB1 receptors, while showing no efficacy against human CB2 receptors. This compound is valuable for research applications involving the endocannabinoid system and its role in various physiological processes.
Chemical Information
| Catalog Num | A59201 |
|---|---|
| M. Wt | 497.38 |
| Formula | C23H20Cl2F2N2O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 358970-97-5 |
| Synonyms | AVE1625 |
| SMILES | CS(=O)(N(C1CN(C(C2=CC=C(Cl)C=C2)C3=CC=C(Cl)C=C3)C1)C4=CC(F)=CC(F)=C4)=O |
Biological Activity
| Description | Drinabant is a potent antagonist of the CB1 receptor, specifically designed for oral activity. It effectively inhibits agonist-stimulated calcium signaling, demonstrating IC50 values of 25 nM for human CB1 receptors and 10 nM for rat CB1 receptors, while showing no efficacy against human CB2 receptors. This compound is valuable for research applications involving the endocannabinoid system and its role in various physiological processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
