Product Data Sheet
LEI-101
Catalog No. A59225
LEI-101 is a selective, orally bioavailable agonist of the cannabinoid CB2 receptor, exhibiting a pEC50 of 8 for human CB2. With a pKi of less than 4 for hERG, it demonstrates minimal off-target activity. This compound is approximately 100-fold more potent in binding to CB2 receptors compared to CB1 receptors, making it a valuable tool for research in pain modulation, inflammation, and neuroprotection studies.
Chemical Information
| Catalog Num | A59225 |
|---|---|
| M. Wt | 508.99 |
| Formula | C23H26ClFN4O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2250025-91-1 |
| Synonyms | |
| SMILES | O=C1N(C2CC2)C(CN1CC3=CC=C(C4=NC(CN5CCS(CC5)(=O)=O)=C(F)C=C4)C=C3)=O.[H]Cl |
Biological Activity
| Description | LEI-101 is a selective, orally bioavailable agonist of the cannabinoid CB2 receptor, exhibiting a pEC50 of 8 for human CB2. With a pKi of less than 4 for hERG, it demonstrates minimal off-target activity. This compound is approximately 100-fold more potent in binding to CB2 receptors compared to CB1 receptors, making it a valuable tool for research in pain modulation, inflammation, and neuroprotection studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
