Product Data Sheet
MJ15
Catalog No. A59231
MJ15 is a potent and selective antagonist of the cannabinoid receptor type 1 (CB1), with a Ki of 27.2 pM and an IC50 of 118.9 pM specifically for rat CB1 receptors. This compound has demonstrated significant biological activity in models of obesity and hyperlipidemia, effectively inhibiting food intake and preventing increases in body weight in diet-induced obese rats and mice. MJ15 is valuable for research applications focused on metabolic disorders and the endocannabinoid system.
Chemical Information
| Catalog Num | A59231 |
|---|---|
| M. Wt | 471.77 |
| Formula | C23H17Cl3N4O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 944154-76-1 |
| Synonyms | |
| SMILES | O=C(C1=NN(C2=CC=C(Cl)C=C2Cl)C(C3=CC=C(Cl)C=C3)=C1C)NCC4=CC=CN=C4 |
Biological Activity
| Description | MJ15 is a potent and selective antagonist of the cannabinoid receptor type 1 (CB1), with a Ki of 27.2 pM and an IC50 of 118.9 pM specifically for rat CB1 receptors. This compound has demonstrated significant biological activity in models of obesity and hyperlipidemia, effectively inhibiting food intake and preventing increases in body weight in diet-induced obese rats and mice. MJ15 is valuable for research applications focused on metabolic disorders and the endocannabinoid system. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
