Product Data Sheet

CB2 receptor agonist 3

Catalog No. A59240

main product photo
CB2 receptor agonist 3 is a highly selective agonist for the CB2 cannabinoid receptor, exhibiting an affinity of 7.6 nM for CB2 and a significantly lower affinity of 900 nM for CB1. This compound effectively activates downstream signaling pathways, as evidenced by its ability to significantly enhance P-ERK 1/2 expression in HL-60 cells. CB2 receptor agonist 3 is valuable for research investigating the role of CB2 receptors in various biological processes and potential therapeutic applications in inflammation and pain management.
Chemical Information
Catalog NumA59240
M. Wt440.36
FormulaC24H23Cl2N3O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.919077-81-9
SynonymsGP2a
SMILESO=C(C1=NN(C2=C1CC3=C2C=CC(C)=C3)C4=CC=C(C=C4Cl)Cl)NC5CCCCC5
Biological Activity
DescriptionCB2 receptor agonist 3 is a highly selective agonist for the CB2 cannabinoid receptor, exhibiting an affinity of 7.6 nM for CB2 and a significantly lower affinity of 900 nM for CB1. This compound effectively activates downstream signaling pathways, as evidenced by its ability to significantly enhance P-ERK 1/2 expression in HL-60 cells. CB2 receptor agonist 3 is valuable for research investigating the role of CB2 receptors in various biological processes and potential therapeutic applications in inflammation and pain management.
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