Product Data Sheet
S-777469
Catalog No. A59246
S-777469 is a selective cannabinoid type 2 receptor (CB2) agonist with a Ki value of 36 nM. This compound exhibits significant antipruritic activity by effectively suppressing compound 48/80-induced scratching behavior in mice in a dose-dependent manner. S-777469 operates by inhibiting itch signal transmission through its action on the CB2 receptor, making it a valuable tool for research in itch modulation and related sensory pathways.
Chemical Information
| Catalog Num | A59246 |
|---|---|
| M. Wt | 414.47 |
| Formula | C23H27FN2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 885496-53-7 |
| Synonyms | |
| SMILES | O=C(C1=CC(C)=C(CC)N(CC2=CC=C(C=C2)F)C1=O)NC3(CCCCC3)C(O)=O |
Biological Activity
| Description | S-777469 is a selective cannabinoid type 2 receptor (CB2) agonist with a Ki value of 36 nM. This compound exhibits significant antipruritic activity by effectively suppressing compound 48/80-induced scratching behavior in mice in a dose-dependent manner. S-777469 operates by inhibiting itch signal transmission through its action on the CB2 receptor, making it a valuable tool for research in itch modulation and related sensory pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
