Product Data Sheet

O-2050

Catalog No. A59268

main product photo
O-2050 is a potent cannabinoid CB1 receptor antagonist with an affinity of Ki = 2.5 nM. In addition, it exhibits significant inhibitory activity at the CB2 receptor with a Ki of 0.2 nM. This compound has been observed to induce locomotor stimulation in murine models, making it relevant for studies exploring the pharmacological effects of cannabinoid signaling in various research applications.
Chemical Information
Catalog NumA59268
M. Wt417.56
FormulaC23H31NO4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1883545-42-3
Synonyms
SMILESCS(=O)(NCCCC#CCC1=CC(O)=C([C@@]2([H])[C@](CC=C(C)C2)([H])C(C)(C)O3)C3=C1)=O
Biological Activity
DescriptionO-2050 is a potent cannabinoid CB1 receptor antagonist with an affinity of Ki = 2.5 nM. In addition, it exhibits significant inhibitory activity at the CB2 receptor with a Ki of 0.2 nM. This compound has been observed to induce locomotor stimulation in murine models, making it relevant for studies exploring the pharmacological effects of cannabinoid signaling in various research applications.
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