Product Data Sheet
BNS808
Catalog No. A59316
BNS808 is a selective antagonist of the cannabinoid-1 receptor (CB1R), demonstrating an IC50 value of 0.8 nM while exhibiting notable selectivity for the CB2 receptor and limited central nervous system penetration. This compound is primarily utilized in research focused on obesity and its related metabolic disorders, including metabolic dysfunction-associated steatotic liver disease (MASLD). BNS808's reduced availability for CNS entry enhances its safety profile and minimizes the potential for drug-drug interactions due to high plasma protein binding.
Chemical Information
| Catalog Num | A59316 |
|---|---|
| M. Wt | 548.87 |
| Formula | C25H20Cl3N3O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2836313-12-1 |
| Synonyms | |
| SMILES | ClC1=CC=C(S(=O)(NC2CCCOC3=C(C4=CC=C(Cl)C=C4)N(C5=C(Cl)C=CC=C5)N=C23)=O)C=C1 |
Biological Activity
| Description | BNS808 is a selective antagonist of the cannabinoid-1 receptor (CB1R), demonstrating an IC50 value of 0.8 nM while exhibiting notable selectivity for the CB2 receptor and limited central nervous system penetration. This compound is primarily utilized in research focused on obesity and its related metabolic disorders, including metabolic dysfunction-associated steatotic liver disease (MASLD). BNS808's reduced availability for CNS entry enhances its safety profile and minimizes the potential for drug-drug interactions due to high plasma protein binding. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
