Product Data Sheet

AM8936

Catalog No. A59360

main product photo
AM8936 is a potent and balanced agonist of the cannabinoid receptor type-1 (CB1), exhibiting EC50 values of 8.6 nM for rat CB1 (rCB1) and 1.4 nM for human CB1 (hCB1). With a high affinity for rCB1 demonstrated by a Ki of 0.55 nM, AM8936 is effective in vivo. This compound is instrumental in research related to central nervous system disorders, metabolic diseases, pain management, and glaucoma.
Chemical Information
Catalog NumA59360
M. Wt395.53
FormulaC25H33NO3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2820337-96-8
Synonyms
SMILESCC1(OC2=C([C@@H]3CC(CC[C@H]31)=O)C(O)=CC(C4(CCC4)CCCCCC#N)=C2)C
Biological Activity
DescriptionAM8936 is a potent and balanced agonist of the cannabinoid receptor type-1 (CB1), exhibiting EC50 values of 8.6 nM for rat CB1 (rCB1) and 1.4 nM for human CB1 (hCB1). With a high affinity for rCB1 demonstrated by a Ki of 0.55 nM, AM8936 is effective in vivo. This compound is instrumental in research related to central nervous system disorders, metabolic diseases, pain management, and glaucoma.
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