Product Data Sheet
GAT229
Catalog No. A59410
GAT229 is a positive allosteric modulator of the CB1 receptor, demonstrating significant potential in the reduction of intraocular pressure (IOP). Research indicates that GAT229 effectively enhances CB1 receptor-mediated IOP-lowering effects in high IOP mouse models. A solution of 0.2% GAT229 or administration at a dosage of 10 mg/kg results in notable IOP reduction, making it a valuable tool for studies focused on glaucoma and related conditions associated with elevated intraocular pressure.
Chemical Information
| Catalog Num | A59410 |
|---|---|
| M. Wt | 342.39 |
| Formula | C22H18N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 889860-85-9 |
| Synonyms | |
| SMILES | O=[N+](C[C@H](C1=C(C2=CC=CC=C2)NC3=C1C=CC=C3)C4=CC=CC=C4)[O-] |
Biological Activity
| Description | GAT229 is a positive allosteric modulator of the CB1 receptor, demonstrating significant potential in the reduction of intraocular pressure (IOP). Research indicates that GAT229 effectively enhances CB1 receptor-mediated IOP-lowering effects in high IOP mouse models. A solution of 0.2% GAT229 or administration at a dosage of 10 mg/kg results in notable IOP reduction, making it a valuable tool for studies focused on glaucoma and related conditions associated with elevated intraocular pressure. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
