Product Data Sheet
MRL-650
Catalog No. A59466
MRL-650 is a potent inverse agonist of the CB1 receptor, exhibiting an IC50 of 7.5 nM for CB1, while maintaining a significantly lower affinity for the CB2 receptor at 4100 nM. This compound is orally active and is primarily utilized in research focused on anorexigenic effects. Its selectivity and potency make MRL-650 a valuable tool for investigating the physiological and pharmacological roles of the endocannabinoid system.
Chemical Information
| Catalog Num | A59466 |
|---|---|
| M. Wt | 514.79 |
| Formula | C25H18Cl3N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 852315-00-5 |
| Synonyms | CB1 inverse agonist 1 |
| SMILES | CC(NC1=C(C(C)=O)C(N(C)C2=NC(C3=CC=C(Cl)C=C3Cl)=C(C4=CC=C(Cl)C=C4)C=C12)=O)=O |
Biological Activity
| Description | MRL-650 is a potent inverse agonist of the CB1 receptor, exhibiting an IC50 of 7.5 nM for CB1, while maintaining a significantly lower affinity for the CB2 receptor at 4100 nM. This compound is orally active and is primarily utilized in research focused on anorexigenic effects. Its selectivity and potency make MRL-650 a valuable tool for investigating the physiological and pharmacological roles of the endocannabinoid system. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
