Product Data Sheet

CCR5/CXCR3-IN-1

Catalog No. A59597

main product photo
CCR5/CXCR3-IN-1 is a potent inhibitor of the chemokine receptors CXCR3 and CCR5. This compound effectively suppresses the chemotaxis of transformed cells expressing CCR5 and CXCR3, while exhibiting no inhibitory effect on CXCR4-expressing transfected cells. CCR5/CXCR3-IN-1 is valuable for research into chronic arthritic rheumatism and other conditions where modulation of these receptors is crucial.
Chemical Information
Catalog NumA59597
M. Wt462.56
FormulaC25H26N4O3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.680203-04-7
Synonyms
SMILESO=C(C1=C(NC(CN2CCN(CC2)C(C3=CC=C(C)C=C3)=O)=O)C=C(C4=CC=CC=C4)S1)N
Biological Activity
DescriptionCCR5/CXCR3-IN-1 is a potent inhibitor of the chemokine receptors CXCR3 and CCR5. This compound effectively suppresses the chemotaxis of transformed cells expressing CCR5 and CXCR3, while exhibiting no inhibitory effect on CXCR4-expressing transfected cells. CCR5/CXCR3-IN-1 is valuable for research into chronic arthritic rheumatism and other conditions where modulation of these receptors is crucial.
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SHIPPING AND STORAGE
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