Product Data Sheet

VL-0395

Catalog No. A59715

main product photo
VL-0395 is a selective antagonist of the cholecystokinin receptor 1 (CCK1), demonstrating an IC50 of 0.197 μM in rat pancreatic acinar cells. This compound effectively inhibits CCK1-mediated signaling pathways, making it a valuable tool for studying the physiological and pathological roles of CCK1 in digestive processes and pancreatic function. Its specificity and potency position VL-0395 as an essential reagent for research in gastrointestinal pharmacology and related fields.
Chemical Information
Catalog NumA59715
M. Wt427.45
FormulaC25H21N3O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.620167-11-5
Synonyms
SMILESO=C(C(CC1=CC=CC=C1)NC(C2=C(NC(C3=CC4=C(N3)C=CC=C4)=O)C=CC=C2)=O)O
Biological Activity
DescriptionVL-0395 is a selective antagonist of the cholecystokinin receptor 1 (CCK1), demonstrating an IC50 of 0.197 μM in rat pancreatic acinar cells. This compound effectively inhibits CCK1-mediated signaling pathways, making it a valuable tool for studying the physiological and pathological roles of CCK1 in digestive processes and pancreatic function. Its specificity and potency position VL-0395 as an essential reagent for research in gastrointestinal pharmacology and related fields.
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