Product Data Sheet
Corticotropin-releasing factor (human)
Catalog No. A59729
Corticotropin-releasing factor (human) acts as a modulator of corticotropin-releasing factor receptors (CRFR). It plays a crucial role in the hypothalamic-pituitary-adrenal (HPA) axis by stimulating the synthesis and secretion of adrenocorticotropin (ACTH) in the anterior pituitary. This reagent is essential for research in stress response, neuroendocrine regulation, and related pathophysiological conditions. Its applications extend to studies in anxiety, depression, and other mood disorders, providing insight into the molecular mechanisms of HPA axis regulation.
Chemical Information
| Catalog Num | A59729 |
|---|---|
| M. Wt | 4757.45 |
| Formula | C208H344N60O63S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 86784-80-7 |
| Synonyms | Human CRF; Human corticotropin-releasing factor |
| SMILES | CCC(C)C(NC(=O)C(NC(=O)C(CCC(O)=O)NC(=O)C(CCSC)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCNC(N)=N)NC(=O)C(CC(N)=O)NC(=O)C(CO)NC(=O)C(Cc1c[nH]cn1)NC(=O)C(C)NC(=O)C(CCC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C)NC(=O)C(CCCNC(N)=N)NC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CCC(O)=O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(O)=O)NC(=O)C(CCCNC(N)=N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(Cc1c[nH]cn1)NC(=O)C(Cc1ccccc1)NC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(CC(O)=O)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(NC(=O)C1CCCN1C(=O)C1CCCN1C(=O)C(CCC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(N)CO)C(C)CC)C(C)O)C(C)C)C(C)CC)C(N)=O |
Biological Activity
| Description | Corticotropin-releasing factor (human) acts as a modulator of corticotropin-releasing factor receptors (CRFR). It plays a crucial role in the hypothalamic-pituitary-adrenal (HPA) axis by stimulating the synthesis and secretion of adrenocorticotropin (ACTH) in the anterior pituitary. This reagent is essential for research in stress response, neuroendocrine regulation, and related pathophysiological conditions. Its applications extend to studies in anxiety, depression, and other mood disorders, providing insight into the molecular mechanisms of HPA axis regulation. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
