Product Data Sheet
ACT-660602
Catalog No. A59782
ACT-660602 is an orally active antagonist of the chemokine receptor CXCR3, demonstrating an IC50 value of 204 nM. This compound effectively inhibits T-cell migration, making it a valuable tool in the study of immune response. ACT-660602 has shown efficacy in models of acute lung injury and is relevant for research focused on autoimmune diseases and related inflammatory conditions.
Chemical Information
| Catalog Num | A59782 |
|---|---|
| M. Wt | 534.48 |
| Formula | C20H20F6N8OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1646267-59-5 |
| Synonyms | |
| SMILES | FC(C1=NC=C(C2=C(N3C[C@@H](C)N(C(CN4N=C(C)N=C4C)=O)CC3)SC(C(F)(F)F)=N2)C=N1)(F)F |
Biological Activity
| Description | ACT-660602 is an orally active antagonist of the chemokine receptor CXCR3, demonstrating an IC50 value of 204 nM. This compound effectively inhibits T-cell migration, making it a valuable tool in the study of immune response. ACT-660602 has shown efficacy in models of acute lung injury and is relevant for research focused on autoimmune diseases and related inflammatory conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
