Product Data Sheet
BVT173187
Catalog No. A59785
BVT173187 is a selective inhibitor of the CXCR target, effectively blocking the activation of the neutrophil formyl peptide receptor FPR1. This compound suppresses FPR1 agonist-induced activation in neutrophils, leading to decreased mobilization of adhesion molecules and reduced superoxide anion production. In addition to its strong effects on FPR1, BVT173187 also influences C5aR and CXCR signaling pathways, making it a valuable tool for research in inflammation and immune response.
Chemical Information
| Catalog Num | A59785 |
|---|---|
| M. Wt | 330.59 |
| Formula | C14H10Cl3NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1374984-75-4 |
| Synonyms | |
| SMILES | O=C(C1=CC(Cl)=CC(Cl)=C1O)NC2=CC(C)=CC=C2Cl |
Biological Activity
| Description | BVT173187 is a selective inhibitor of the CXCR target, effectively blocking the activation of the neutrophil formyl peptide receptor FPR1. This compound suppresses FPR1 agonist-induced activation in neutrophils, leading to decreased mobilization of adhesion molecules and reduced superoxide anion production. In addition to its strong effects on FPR1, BVT173187 also influences C5aR and CXCR signaling pathways, making it a valuable tool for research in inflammation and immune response. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
