Product Data Sheet
CXCR6 antagonist 1
Catalog No. A59805
CXCR6 antagonist 1 is a selective antagonist of the CXCR6 receptor, which plays a critical role in immune cell trafficking and tumor microenvironment modulation. This compound effectively inhibits CXCR6-mediated signaling pathways, including β-arrestin recruitment and cAMP production induced by Forskolin. Additionally, CXCR6 antagonist 1 demonstrates significant efficacy in reducing tumor growth in a mouse xenograft model of hepatocellular carcinoma. It is a valuable tool for research applications focused on hepatocellular carcinoma and therapeutic strategies targeting CXCR6.
Chemical Information
| Catalog Num | A59805 |
|---|---|
| M. Wt | 549.61 |
| Formula | C27H30F3N3O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2579689-85-1 |
| Synonyms | |
| SMILES | C(N1[C@@]2(C[C@H](NC(=O)C3=CC(OC)=C(OC)C(OC)=C3)C[C@]1(CCC2)[H])[H])C4=NC=5C(S4)=CC=CC5C(F)(F)F |
Biological Activity
| Description | CXCR6 antagonist 1 is a selective antagonist of the CXCR6 receptor, which plays a critical role in immune cell trafficking and tumor microenvironment modulation. This compound effectively inhibits CXCR6-mediated signaling pathways, including β-arrestin recruitment and cAMP production induced by Forskolin. Additionally, CXCR6 antagonist 1 demonstrates significant efficacy in reducing tumor growth in a mouse xenograft model of hepatocellular carcinoma. It is a valuable tool for research applications focused on hepatocellular carcinoma and therapeutic strategies targeting CXCR6. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
