Product Data Sheet

ACT-672125

Catalog No. A59820

main product photo
ACT-672125 is a potent antagonist of the CXCR3 receptor, exhibiting an IC50 value of 239 nM in human blood. Additionally, it shows hERG activity with an IC50 of 18 μM. This compound is primarily utilized in research investigating autoimmune diseases, providing insights into the modulation of immune responses.
Chemical Information
Catalog NumA59820
M. Wt586.59
FormulaC25H25F3N10O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1449367-94-5
Synonyms
SMILESFC(F)(C1=NC(C2=NC3=CC=C(C4=NOC(C)=N4)C=C3N2)=C(N5C[C@H](N(CC5)C(CN6C(C)=NC(C)=N6)=O)C)S1)F
Biological Activity
DescriptionACT-672125 is a potent antagonist of the CXCR3 receptor, exhibiting an IC50 value of 239 nM in human blood. Additionally, it shows hERG activity with an IC50 of 18 μM. This compound is primarily utilized in research investigating autoimmune diseases, providing insights into the modulation of immune responses.
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