Product Data Sheet

Pramipexole

Catalog No. A59857

main product photo
Pramipexole is a selective dopamine D2-type receptor agonist that effectively penetrates the blood-brain barrier. It exhibits high affinity with Kis of 2.2 nM for the D2-type receptor, 3.9 nM for D2, 0.5 nM for D3, and 1.3 nM for D4 receptors. This compound is utilized in research related to Parkinson's disease and restless legs syndrome, supporting studies aimed at understanding and treating these neurological disorders.
Chemical Information
Catalog NumA59857
M. Wt211.33
FormulaC10H17N3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.104632-26-0
Synonyms
SMILESNC1=NC(CC[C@H](NCCC)C2)=C2S1
Biological Activity
DescriptionPramipexole is a selective dopamine D2-type receptor agonist that effectively penetrates the blood-brain barrier. It exhibits high affinity with Kis of 2.2 nM for the D2-type receptor, 3.9 nM for D2, 0.5 nM for D3, and 1.3 nM for D4 receptors. This compound is utilized in research related to Parkinson's disease and restless legs syndrome, supporting studies aimed at understanding and treating these neurological disorders.
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