Product Data Sheet
NGD94-1
Catalog No. A59925
NGD94-1 is a potent and selective antagonist of the dopamine D4 receptor, exhibiting high affinity for the human D4.2 receptor (Ki = 3.6 nM). This compound plays a significant role in modulating cognitive functions within the frontostriatal system and regulates dopaminergic transmission, particularly in Phencyclidine (PCP)-induced models. NGD94-1 is suitable for applications in neurological disease research, providing valuable insights into dopaminergic mechanisms and their impact on cognition.
Chemical Information
| Catalog Num | A59925 |
|---|---|
| M. Wt | 320.39 |
| Formula | C18H20N6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 178928-68-2 |
| Synonyms | |
| SMILES | C1(N2CCN(CC3=CN=C(C4=CC=CC=C4)N3)CC2)=NC=CC=N1 |
Biological Activity
| Description | NGD94-1 is a potent and selective antagonist of the dopamine D4 receptor, exhibiting high affinity for the human D4.2 receptor (Ki = 3.6 nM). This compound plays a significant role in modulating cognitive functions within the frontostriatal system and regulates dopaminergic transmission, particularly in Phencyclidine (PCP)-induced models. NGD94-1 is suitable for applications in neurological disease research, providing valuable insights into dopaminergic mechanisms and their impact on cognition. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
