Product Data Sheet
Pramipexole-d5
Catalog No. A60008
Pramipexole-d5 is a deuterium-labeled derivative of Pramipexole, a selective dopamine D2-type receptor agonist that effectively crosses the blood-brain barrier. With binding affinities (Kis) of 2.2 nM, 3.9 nM, 0.5 nM, and 1.3 nM for the D2-type, D2, D3, and D4 receptors respectively, Pramipexole-d5 serves as a valuable tool for exploring dopamine receptor interactions. This compound is particularly relevant for research into neurodegenerative disorders such as Parkinson's disease and conditions like restless legs syndrome.
Chemical Information
| Catalog Num | A60008 |
|---|---|
| M. Wt | 216.36 |
| Formula | C10H12D5N3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1217975-28-4 |
| Synonyms | |
| SMILES | NC1=NC2=C(S1)C[C@H](CC2)NCC([2H])([2H])C([2H])([2H])[2H] |
Biological Activity
| Description | Pramipexole-d5 is a deuterium-labeled derivative of Pramipexole, a selective dopamine D2-type receptor agonist that effectively crosses the blood-brain barrier. With binding affinities (Kis) of 2.2 nM, 3.9 nM, 0.5 nM, and 1.3 nM for the D2-type, D2, D3, and D4 receptors respectively, Pramipexole-d5 serves as a valuable tool for exploring dopamine receptor interactions. This compound is particularly relevant for research into neurodegenerative disorders such as Parkinson's disease and conditions like restless legs syndrome. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
