Product Data Sheet
ABT-724
Catalog No. A60163
ABT-724 is a potent and highly selective agonist of the dopamine D4 receptor, exhibiting an EC50 of 12.4 nM for the human receptor. It also demonstrates efficacy as a partial agonist at the rat and ferret D4 receptors, with EC50 values of 14.3 nM and 23.2 nM, respectively. ABT-724 shows minimal activity against dopamine D1, D2, D3, and D5 receptors, making it a valuable tool for exploring the role of the D4 receptor in neurological conditions and potential therapeutic applications for erectile dysfunction.
Chemical Information
| Catalog Num | A60163 |
|---|---|
| M. Wt | 293.37 |
| Formula | C17H19N5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 70006-24-5 |
| Synonyms | |
| SMILES | C1(NC(CN2CCN(C3=NC=CC=C3)CC2)=N4)=C4C=CC=C1 |
Biological Activity
| Description | ABT-724 is a potent and highly selective agonist of the dopamine D4 receptor, exhibiting an EC50 of 12.4 nM for the human receptor. It also demonstrates efficacy as a partial agonist at the rat and ferret D4 receptors, with EC50 values of 14.3 nM and 23.2 nM, respectively. ABT-724 shows minimal activity against dopamine D1, D2, D3, and D5 receptors, making it a valuable tool for exploring the role of the D4 receptor in neurological conditions and potential therapeutic applications for erectile dysfunction. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
