Ropinirole-d4 hydrochloride
Catalog No. A60167

Ropinirole-d4 hydrochloride is a deuterium-labeled derivative of Ropinirole hydrochloride, functioning primarily as a selective D2/D3 receptor agonist. It exhibits a Kiof of 29 nM for the D2 receptor and demonstrates pEC50 values of 7.4, 8.4, and 6.8 for human D2, D3, and D4 receptors, respectively. With its specific action and lack of affinity for D1 receptors, Ropinirole-d4 is particularly valuable in investigations related to Parkinson's disease and receptor pharmacology.
Chemical Information
| Catalog Num | A60167 |
|---|---|
| M. Wt | 300.86 |
| Formula | C16H21D4ClN2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1330261-37-4 |
| Synonyms | SKF 101468-d4 hydrochloride |
| SMILES | C(CN(C(CC)([2H])[2H])C(CC)([2H])[2H])C1=C2C(NC(=O)C2)=CC=C1.Cl |
Biological Activity
| Description | Ropinirole-d4 hydrochloride is a deuterium-labeled derivative of Ropinirole hydrochloride, functioning primarily as a selective D2/D3 receptor agonist. It exhibits a Kiof of 29 nM for the D2 receptor and demonstrates pEC50 values of 7.4, 8.4, and 6.8 for human D2, D3, and D4 receptors, respectively. With its specific action and lack of affinity for D1 receptors, Ropinirole-d4 is particularly valuable in investigations related to Parkinson's disease and receptor pharmacology. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


