Product Data Sheet
Ropinirole-d14 hydrochloride
Catalog No. A60170
Ropinirole-d14 hydrochloride is a deuterated analog of Ropinirole hydrochloride, functioning primarily as a D3/D2 receptor agonist. It exhibits a Ki value of 29 nM for the D2 receptor and pEC50 values of 7.4, 8.4, and 6.8 for human D2, D3, and D4 receptors, respectively. This compound is instrumental in studying Parkinson's disease due to its targeted pharmacological activity and lack of affinity for D1 receptors, making it a valuable tool in neuropharmacological research.
Chemical Information
| Catalog Num | A60170 |
|---|---|
| M. Wt | 310.92 |
| Formula | C16H11D14ClN2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1276197-10-4 |
| Synonyms | SKF 101468-d14 hydrochloride |
| SMILES | [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])CCC1=C2C(NC(C2)=O)=CC=C1.Cl |
Biological Activity
| Description | Ropinirole-d14 hydrochloride is a deuterated analog of Ropinirole hydrochloride, functioning primarily as a D3/D2 receptor agonist. It exhibits a Ki value of 29 nM for the D2 receptor and pEC50 values of 7.4, 8.4, and 6.8 for human D2, D3, and D4 receptors, respectively. This compound is instrumental in studying Parkinson's disease due to its targeted pharmacological activity and lack of affinity for D1 receptors, making it a valuable tool in neuropharmacological research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
