Product Data Sheet
Raclopride-d5 hydrochloride
Catalog No. A60207
Raclopride-d5 hydrochloride is a deuterium-labeled derivative of Raclopride, a selective antagonist for dopamine D2 and D3 receptors. It exhibits high affinity, with dissociation constants (Kis) of 1.8 nM for D2 and 3.5 nM for D3 receptors, while demonstrating minimal interaction with D1 and D4 receptors (Kis of 18000 nM and 2400 nM, respectively). This compound is valuable in neuropharmacology research for studying dopamine signaling pathways and receptor mechanisms in various models.
Chemical Information
| Catalog Num | A60207 |
|---|---|
| M. Wt | 352.27 |
| Formula | C15H16D5Cl3N2O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1217623-85-2 |
| Synonyms | |
| SMILES | C(NC[C@H]1N(C(C([2H])([2H])[2H])([2H])[2H])CCC1)(=O)C2=C(OC)C(Cl)=CC(Cl)=C2O.Cl |
Biological Activity
| Description | Raclopride-d5 hydrochloride is a deuterium-labeled derivative of Raclopride, a selective antagonist for dopamine D2 and D3 receptors. It exhibits high affinity, with dissociation constants (Kis) of 1.8 nM for D2 and 3.5 nM for D3 receptors, while demonstrating minimal interaction with D1 and D4 receptors (Kis of 18000 nM and 2400 nM, respectively). This compound is valuable in neuropharmacology research for studying dopamine signaling pathways and receptor mechanisms in various models. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
