Product Data Sheet

Clazosentan

Catalog No. A60240

main product photo
Clazosentan is a selective endothelin A (ETA) receptor antagonist. It effectively inhibits ET-1-mediated vasoconstriction, making it a valuable tool in research focused on cardiovascular function and cerebral health. Clazosentan is primarily utilized in studies investigating the prevention of cerebral vasospasm and associated complications, including cerebral infarction.
Chemical Information
Catalog NumA60240
M. Wt577.57
FormulaC25H23N9O6S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.180384-56-9
SynonymsRo 61-1790; VML 588; AXV-034343
SMILESO=S(C1=NC=C(C)C=C1)(NC2=NC(C3=CC(C4=NNN=N4)=NC=C3)=NC(OCCO)=C2OC5=CC=CC=C5OC)=O
Biological Activity
DescriptionClazosentan is a selective endothelin A (ETA) receptor antagonist. It effectively inhibits ET-1-mediated vasoconstriction, making it a valuable tool in research focused on cardiovascular function and cerebral health. Clazosentan is primarily utilized in studies investigating the prevention of cerebral vasospasm and associated complications, including cerebral infarction.
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