Product Data Sheet
JKC 302
Catalog No. A60261
JKC 302 is an endothelin-1 (ET-1) receptor type A (ET-A) antagonist that inhibits ET-1-induced contraction in asthmatic rat trachea rings. This compound serves as a valuable tool for studying the role of endothelin signaling in respiratory conditions and may aid in the development of therapeutic strategies for asthma and related disorders. Its application in research provides insights into the mechanisms underlying airway hyperreactivity and constriction.
Chemical Information
| Catalog Num | A60261 |
|---|---|
| M. Wt | 582.69 |
| Formula | C30H42N6O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 153982-38-8 |
| Synonyms | |
| SMILES | C(C=1C=2C(NC1)=CC=CC2)[C@@H]3C(=O)N[C@H](CO)C(=O)N4[C@](C(=O)N[C@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N3)(CCC4)[H] |
Biological Activity
| Description | JKC 302 is an endothelin-1 (ET-1) receptor type A (ET-A) antagonist that inhibits ET-1-induced contraction in asthmatic rat trachea rings. This compound serves as a valuable tool for studying the role of endothelin signaling in respiratory conditions and may aid in the development of therapeutic strategies for asthma and related disorders. Its application in research provides insights into the mechanisms underlying airway hyperreactivity and constriction. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
