Product Data Sheet
[Ala2] Endothelin-3, human
Catalog No. A60276
[Ala2] Endothelin-3 (ET-3) is a vasoactive peptide analog of endothelin-3, featuring alanine substitutions for cysteine residues. This peptide is primarily produced by human rhabdomyosarcoma cell lines and plays a crucial role in paracrine signaling by promoting endothelial cell migration. Research applications include studies on vascular biology, endothelial function, and the pathophysiology of muscle-origin tumors.
Chemical Information
| Catalog Num | A60276 |
|---|---|
| M. Wt | 2613.02 |
| Formula | C120H166N26O32S4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2243207-08-9 |
| Synonyms | |
| SMILES | C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CN=CN1)NC(=O)[C@H]2NC(=O)[C@H](CC3=CC=C(O)C=C3)NC(=O)[C@H](CC4=CC=C(O)C=C4)NC(=O)[C@H]([C@H](C)C)NC(=O)[C@]5(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC6=CC=C(O)C=C6)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CC7=CC=CC=C7)NC(=O)[C@@](NC(=O)[C@H](C)NC(=O)[C@@H](N)CSSC2)(CSSC5)[H])[H])[H])=O)CC(C)C)=O)CC(O)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)C(O)=O)C=8C=9C(NC8)=CC=CC9 |
Biological Activity
| Description | [Ala2] Endothelin-3 (ET-3) is a vasoactive peptide analog of endothelin-3, featuring alanine substitutions for cysteine residues. This peptide is primarily produced by human rhabdomyosarcoma cell lines and plays a crucial role in paracrine signaling by promoting endothelial cell migration. Research applications include studies on vascular biology, endothelial function, and the pathophysiology of muscle-origin tumors. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
