Product Data Sheet

Aselacin B

Catalog No. A60290

main product photo
Aselacin B is an endothelin-1 receptor antagonist that inhibits the binding of endothelin-1 to both ETA and ETB receptors. This compound plays a significant role in the investigation of cardiovascular diseases by modulating endothelin signaling pathways. Its application may provide insights into the pathophysiology of conditions such as hypertension and heart failure.
Chemical Information
Catalog NumA60290
M. Wt923.06
FormulaC46H66N8O12
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.156223-07-3
Synonyms
SMILESO=C1O[C@@H]([C@@H](C(NCCC(N[C@H](CC2=CNC3=C2C=CC=C3)C(N[C@H](CO)C(NC1)=O)=O)=O)=O)NC(C(CCC(N)=O)NC(CCCCCCCC(/C=C/C=C/CCCC(C)O)=O)=O)=O)C
Biological Activity
DescriptionAselacin B is an endothelin-1 receptor antagonist that inhibits the binding of endothelin-1 to both ETA and ETB receptors. This compound plays a significant role in the investigation of cardiovascular diseases by modulating endothelin signaling pathways. Its application may provide insights into the pathophysiology of conditions such as hypertension and heart failure.
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