Product Data Sheet
Aselacin A
Catalog No. A60300
Aselacin A is an endothelin-1 receptor (ET-1 receptor) antagonist that effectively inhibits the binding of endothelin-1 to both ETA and ETB receptors. Demonstrating IC50 values of 22 μg/mL and 20 μg/mL, it inhibits ET-1 binding to bovine atrial and porcine cerebral membranes, respectively. This compound is valuable for research into cardiovascular diseases and exploring the pathological roles of endothelin signaling in various cardiovascular conditions.
Chemical Information
| Catalog Num | A60300 |
|---|---|
| M. Wt | 909.08 |
| Formula | C46H68N8O11 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 156223-06-2 |
| Synonyms | |
| SMILES | O=C1O[C@@H]([C@@H](C(NCCC(N[C@H](CC2=CNC3=C2C=CC=C3)C(N[C@H](CO)C(NC1)=O)=O)=O)=O)NC([C@@H](CCC(N)=O)NC(CCCCCCCC(/C=C/C=C/CCCCC)O)=O)=O)C |
Biological Activity
| Description | Aselacin A is an endothelin-1 receptor (ET-1 receptor) antagonist that effectively inhibits the binding of endothelin-1 to both ETA and ETB receptors. Demonstrating IC50 values of 22 μg/mL and 20 μg/mL, it inhibits ET-1 binding to bovine atrial and porcine cerebral membranes, respectively. This compound is valuable for research into cardiovascular diseases and exploring the pathological roles of endothelin signaling in various cardiovascular conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
