Product Data Sheet
FPR2 agonist 3
Catalog No. A60311
FPR2 Agonist 3 (compound CMC23) targets the formyl peptide receptor 2 (FPR2) to exhibit potent anti-inflammatory effects. This compound effectively limits lactate dehydrogenase release in LPS-stimulated cultures and reduces the secretion of pro-inflammatory cytokines IL-1β and IL-6. Additionally, FPR2 Agonist 3 downregulates phosphorylated STAT3 through the STAT3/SOCS3 signaling pathway, making it a valuable tool for research in inflammation and related signaling processes.
Chemical Information
| Catalog Num | A60311 |
|---|---|
| M. Wt | 446.45 |
| Formula | C25H20F2N4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2829263-19-4 |
| Synonyms | |
| SMILES | FC1=CC=C(NC(N[C@@H](CC2=CC=C(C#N)C=C2)C(N3C(C=C(F)C=C4)=C4CC3)=O)=O)C=C1 |
Biological Activity
| Description | FPR2 Agonist 3 (compound CMC23) targets the formyl peptide receptor 2 (FPR2) to exhibit potent anti-inflammatory effects. This compound effectively limits lactate dehydrogenase release in LPS-stimulated cultures and reduces the secretion of pro-inflammatory cytokines IL-1β and IL-6. Additionally, FPR2 Agonist 3 downregulates phosphorylated STAT3 through the STAT3/SOCS3 signaling pathway, making it a valuable tool for research in inflammation and related signaling processes. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
