Product Data Sheet
AH-7614
Catalog No. A60325
AH-7614 is a selective antagonist of FFA4 (GPR120), exhibiting potent inhibition with pIC50 values of 7.1, 8.1, and 8.1 for human, mouse, and rat FFA4, respectively. This compound demonstrates high specificity for FFA4 over FFA1, with a pIC50 value lower than 4.6. AH-7614 effectively blocks the biological effects induced by both linoleic acid, a polyunsaturated ω-6 fatty acid, and synthetic FFA4 agonists, making it a valuable tool for research on metabolic processes and signaling pathways associated with fat metabolism.
Chemical Information
| Catalog Num | A60325 |
|---|---|
| M. Wt | 351.42 |
| Formula | C20H17NO3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 6326-06-3 |
| Synonyms | |
| SMILES | O=S(C1=CC=C(C)C=C1)(NC2C3=C(OC4=C2C=CC=C4)C=CC=C3)=O |
Biological Activity
| Description | AH-7614 is a selective antagonist of FFA4 (GPR120), exhibiting potent inhibition with pIC50 values of 7.1, 8.1, and 8.1 for human, mouse, and rat FFA4, respectively. This compound demonstrates high specificity for FFA4 over FFA1, with a pIC50 value lower than 4.6. AH-7614 effectively blocks the biological effects induced by both linoleic acid, a polyunsaturated ω-6 fatty acid, and synthetic FFA4 agonists, making it a valuable tool for research on metabolic processes and signaling pathways associated with fat metabolism. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
