Product Data Sheet
MK-8666
Catalog No. A60326
MK-8666 is a potent and selective partial agonist of GPR40, with an EC50 of 0.54 nM for human GPR40. This compound exhibits significant selectivity over other G-protein-coupled receptors, including GPR119, GPR43, GPR41, and GPR120. MK-8666 has demonstrated the ability to lower glucose levels in rodent models, making it a valuable tool in type 2 diabetes research and related metabolic studies.
Chemical Information
| Catalog Num | A60326 |
|---|---|
| M. Wt | 521.62 |
| Formula | C29H31NO6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1544739-75-4 |
| Synonyms | |
| SMILES | O=C(O)[C@H]1[C@]([H])(CC2=C3C=NC(OCC4=CC(C5=C(C=C(C=C5C)OCCCS(=O)(C)=O)C)=CC=C4)=C2)[C@@]13[H] |
Biological Activity
| Description | MK-8666 is a potent and selective partial agonist of GPR40, with an EC50 of 0.54 nM for human GPR40. This compound exhibits significant selectivity over other G-protein-coupled receptors, including GPR119, GPR43, GPR41, and GPR120. MK-8666 has demonstrated the ability to lower glucose levels in rodent models, making it a valuable tool in type 2 diabetes research and related metabolic studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
