Product Data Sheet
TUG-469
Catalog No. A60337
TUG-469 is a selective agonist of the free fatty acid receptor 1 (FFA1/GPR40) with an EC50 value of 19 nM, demonstrating over 200-fold selectivity for FFA1 compared to FFA4. This compound has been shown to significantly enhance glucose tolerance in pre-diabetic mouse models. TUG-469 serves as a valuable tool for research into diabetes and metabolic disorders, advancing the understanding of FFA1 signaling in glucose homeostasis.
Chemical Information
| Catalog Num | A60337 |
|---|---|
| M. Wt | 345.43 |
| Formula | C23H23NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1236109-67-3 |
| Synonyms | |
| SMILES | O=C(CCC1=CC=C(C=C1)NCC2=CC(C3=CC=CC=C3C)=CC=C2)O |
Biological Activity
| Description | TUG-469 is a selective agonist of the free fatty acid receptor 1 (FFA1/GPR40) with an EC50 value of 19 nM, demonstrating over 200-fold selectivity for FFA1 compared to FFA4. This compound has been shown to significantly enhance glucose tolerance in pre-diabetic mouse models. TUG-469 serves as a valuable tool for research into diabetes and metabolic disorders, advancing the understanding of FFA1 signaling in glucose homeostasis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
