Product Data Sheet
TUG-499
Catalog No. A60340
TUG-499 is a selective agonist of the free fatty acid receptor 1 (FFAR1 or GPR40), showcasing a pEC50 of 7.39. This compound demonstrates over 100-fold selectivity against related receptors, including FFA2, FFA3, and PPARγ, as well as other receptors, ion channels, and transporters. TUG-499 serves as a valuable tool in the investigation of type 2 diabetes and features an alkyne group, enabling its use in click chemistry applications through copper-catalyzed azide-alkyne cycloaddition (CuAAc).
Chemical Information
| Catalog Num | A60340 |
|---|---|
| M. Wt | 320.17 |
| Formula | C16H11Cl2NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1206629-08-4 |
| Synonyms | |
| SMILES | O=C(O)CCC1=CC=C(C#CC2=CC(Cl)=NC(Cl)=C2)C=C1 |
Biological Activity
| Description | TUG-499 is a selective agonist of the free fatty acid receptor 1 (FFAR1 or GPR40), showcasing a pEC50 of 7.39. This compound demonstrates over 100-fold selectivity against related receptors, including FFA2, FFA3, and PPARγ, as well as other receptors, ion channels, and transporters. TUG-499 serves as a valuable tool in the investigation of type 2 diabetes and features an alkyne group, enabling its use in click chemistry applications through copper-catalyzed azide-alkyne cycloaddition (CuAAc). |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
