Product Data Sheet
FFA2 agonist-1
Catalog No. A60360
FFA2 Agonist-1 is a selective agonist for the Free Fatty Acid Receptor 2 (FFA2/GPR43), exhibiting an EC50 of 81 nM. This compound effectively engages β-arrestin-2 in recruitment assays and demonstrates cAMP inhibition with EC50 values of 1.2 μM and 0.53 μM, respectively. FFA2 Agonist-1 has been shown to influence appetite regulation through peptide YY (PYY) mucosal responses, limiting fat accumulation and impacting intestinal functions and food intake. It is a valuable tool for obesity research and related metabolic studies.
Chemical Information
| Catalog Num | A60360 |
|---|---|
| M. Wt | 435.90 |
| Formula | C25H22ClNO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1312799-06-6 |
| Synonyms | |
| SMILES | O=C(C1=CC=C(C2=C(C=CC=C2)OC)C=C1)N3[C@@H](C4=C(C=CC=C4)Cl)CC[C@H]3C(O)=O |
Biological Activity
| Description | FFA2 Agonist-1 is a selective agonist for the Free Fatty Acid Receptor 2 (FFA2/GPR43), exhibiting an EC50 of 81 nM. This compound effectively engages β-arrestin-2 in recruitment assays and demonstrates cAMP inhibition with EC50 values of 1.2 μM and 0.53 μM, respectively. FFA2 Agonist-1 has been shown to influence appetite regulation through peptide YY (PYY) mucosal responses, limiting fat accumulation and impacting intestinal functions and food intake. It is a valuable tool for obesity research and related metabolic studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
