Product Data Sheet

(R)-AM-1638

Catalog No. A60362

main product photo
(R)-AM-1638 is a R-isomer of AM-1638 and acts as a full agonist of the GPR40 receptor, exhibiting an EC50 of 0.16 μM. This compound plays a significant role in mediating glucose-dependent insulin secretion and is of particular interest in diabetes research. Its selectivity for GPR40 positions it as a valuable tool for studying metabolic disorders and potential therapeutic interventions.
Chemical Information
Catalog NumA60362
M. Wt514.63
FormulaC33H35FO4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1142222-18-1
Synonyms
SMILESFC1=CC=C(OC)C=C1C2=C(C3=CCCC3(C)C)C=C(C=C2)COC4=CC([C@@H](C5CC5)CC(O)=O)=CC=C4
Biological Activity
Description(R)-AM-1638 is a R-isomer of AM-1638 and acts as a full agonist of the GPR40 receptor, exhibiting an EC50 of 0.16 μM. This compound plays a significant role in mediating glucose-dependent insulin secretion and is of particular interest in diabetes research. Its selectivity for GPR40 positions it as a valuable tool for studying metabolic disorders and potential therapeutic interventions.
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