Product Data Sheet
Fasiglifam hemihydrate
Catalog No. A60383
Fasiglifam hemihydrate is a potent and selective agonist of the GPR40 receptor, exhibiting an EC50 value of 72 nM. This compound enhances glucose-dependent insulin secretion and has demonstrated efficacy in reducing hyperglycemia in type 2 diabetic rat models. It is important to note that Fasiglifam may also induce liver injury, warranting careful consideration in research applications.
Chemical Information
| Catalog Num | A60383 |
|---|---|
| M. Wt | 533.63 |
| Formula | C29H33O7.5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1374598-80-7 |
| Synonyms | TAK-875 hemihydrate |
| SMILES | CC1=C(C(C)=CC(OCCCS(C)(=O)=O)=C1)C2=CC(COC3=CC=C4[C@@H](COC4=C3)CC(O)=O)=CC=C2.[0.5H2O] |
Biological Activity
| Description | Fasiglifam hemihydrate is a potent and selective agonist of the GPR40 receptor, exhibiting an EC50 value of 72 nM. This compound enhances glucose-dependent insulin secretion and has demonstrated efficacy in reducing hyperglycemia in type 2 diabetic rat models. It is important to note that Fasiglifam may also induce liver injury, warranting careful consideration in research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
