Product Data Sheet
TGR5 Receptor Agonist 4
Catalog No. A60394
TGR5 Receptor Agonist 4 is a potent agonist of the bile acid receptor TGR5, exhibiting an EC50 of 2 nM for human TGR5 and 3 nM for mouse TGR5. This compound is instrumental in studies focusing on glucose metabolism and weight management. Its activation of TGR5 contributes to hypoglycemic effects and enhances energy expenditure, making it valuable for research in metabolic disorders.
Chemical Information
| Catalog Num | A60394 |
|---|---|
| M. Wt | 470.95 |
| Formula | C25H27ClN2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1872436-42-4 |
| Synonyms | |
| SMILES | COC(C=CC=C1)=C1COC(C([C@H](C2=CN=C(Cl)C=C2)C3)=C(C)N(C[C@H]4CCCO4)C3=O)=O |
Biological Activity
| Description | TGR5 Receptor Agonist 4 is a potent agonist of the bile acid receptor TGR5, exhibiting an EC50 of 2 nM for human TGR5 and 3 nM for mouse TGR5. This compound is instrumental in studies focusing on glucose metabolism and weight management. Its activation of TGR5 contributes to hypoglycemic effects and enhances energy expenditure, making it valuable for research in metabolic disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
