Product Data Sheet
TGR5 Receptor Agonist 3
Catalog No. A60397
TGR5 Receptor Agonist 3 (Compound 19) is a selective agonist for the G-protein-coupled bile acid receptor 1 (TGR5), demonstrating enhanced safety by minimizing gallbladder-filling effects. It exhibits effective activation of human TGR5 with an EC50 of 16.4 nM and mouse TGR5 with an EC50 of 209 nM. This compound is valuable in research applications focusing on metabolic regulation, energy expenditure, and bile acid signaling pathways.
Chemical Information
| Catalog Num | A60397 |
|---|---|
| M. Wt | 513.54 |
| Formula | C29H27N3O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2643391-08-4 |
| Synonyms | |
| SMILES | CCOCOC(C1=COC2=C1C=C(C=C2)OC3=C(C=NC=C3)C(N4CCN(C5=C4C=CC=C5)C6CC6)=O)=O |
Biological Activity
| Description | TGR5 Receptor Agonist 3 (Compound 19) is a selective agonist for the G-protein-coupled bile acid receptor 1 (TGR5), demonstrating enhanced safety by minimizing gallbladder-filling effects. It exhibits effective activation of human TGR5 with an EC50 of 16.4 nM and mouse TGR5 with an EC50 of 209 nM. This compound is valuable in research applications focusing on metabolic regulation, energy expenditure, and bile acid signaling pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
