Product Data Sheet

5-HT7R antagonist 1 free base

Catalog No. A60405

main product photo
5-HT7R antagonist 1 (free base) is a selective antagonist of the serotonin 5-HT7 receptor, exhibiting a Ki value of 6.5 nM. This compound functions as a G protein-biased antagonist, modulating signaling pathways mediated by this receptor. It is primarily utilized in research applications focused on neuropharmacology and exploring the role of 5-HT7R in various physiological and pathological processes.
Chemical Information
Catalog NumA60405
M. Wt276.76
FormulaC14H17ClN4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2337008-64-5
Synonyms
SMILESClC1=CC(C2=NNC=C2N3CCNCCC3)=CC=C1
Biological Activity
Description5-HT7R antagonist 1 (free base) is a selective antagonist of the serotonin 5-HT7 receptor, exhibiting a Ki value of 6.5 nM. This compound functions as a G protein-biased antagonist, modulating signaling pathways mediated by this receptor. It is primarily utilized in research applications focused on neuropharmacology and exploring the role of 5-HT7R in various physiological and pathological processes.
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