Product Data Sheet

Hyodeoxycholic acid sodium

Catalog No. A60408

main product photo
Hyodeoxycholic acid sodium is a potent agonist of the G protein-coupled bile acid receptor 1 (GPBAR1, also known as TGR5). It is a secondary bile acid produced in the small intestine by gut microbiota, demonstrating biological activity with an EC50 of 31.6 µM in Chinese Hamster Ovary (CHO) cells. This compound is valuable for research applications focused on metabolic regulation and signaling pathways associated with bile acids.
Chemical Information
Catalog NumA60408
M. Wt414.55
FormulaC24H39NaO4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.10421-49-5
SynonymsHDCA sodium
SMILESC[C@@H]([C@H]1CC[C@]2([C@@]3(C[C@@H]([C@@]4(C[C@@H](CC[C@@]4([C@]3(CC[C@]12C)[H])C)O)[H])O)[H])[H])CCC(O[Na])=O
Biological Activity
DescriptionHyodeoxycholic acid sodium is a potent agonist of the G protein-coupled bile acid receptor 1 (GPBAR1, also known as TGR5). It is a secondary bile acid produced in the small intestine by gut microbiota, demonstrating biological activity with an EC50 of 31.6 µM in Chinese Hamster Ovary (CHO) cells. This compound is valuable for research applications focused on metabolic regulation and signaling pathways associated with bile acids.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.