Product Data Sheet

LT-188A

Catalog No. A60410

main product photo
LT-188A is a potent agonist of TGR5, exhibiting an EC50 value of 23 μM. This compound has been shown to reduce the levels of inflammatory mediators in macrophages, suggesting its potential utility in inflammation-related research. Its role in modulating immune responses makes LT-188A valuable for investigating TGR5-related pathways and therapeutic applications in inflammatory diseases.
Chemical Information
Catalog NumA60410
M. Wt484.58
FormulaC28H36O7
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2922530-99-0
Synonyms
SMILESCOC1=C(OC)C=C(C[C@H]2CO[C@H](C3=CC(OC)=C(OC)C=C3)[C@H]2CCOC(/C(C)=C\C)=O)C=C1
Biological Activity
DescriptionLT-188A is a potent agonist of TGR5, exhibiting an EC50 value of 23 μM. This compound has been shown to reduce the levels of inflammatory mediators in macrophages, suggesting its potential utility in inflammation-related research. Its role in modulating immune responses makes LT-188A valuable for investigating TGR5-related pathways and therapeutic applications in inflammatory diseases.
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