Product Data Sheet

GLP-1R agonist 18

Catalog No. A60616

main product photo
GLP-1R Agonist 18 is a potent agonist for the glucagon-like peptide-1 receptor (GLP-1R), exhibiting an EC50 of 0.044 nM. This compound enhances insulin secretion in response to glucose, making it a valuable tool for research in diabetes and metabolic disorders. Its high affinity for GLP-1R positions it as a significant candidate for investigating therapeutic strategies targeting glucose homeostasis and appetite regulation.
Chemical Information
Catalog NumA60616
M. Wt641.01
FormulaC32H25ClF4N4O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2855243-02-4
Synonyms
SMILESFC1=C2C(N([C@H]3C(C)(COC3)C)C(CC4=C(C=C(C5=NC(OCC6=C(C=C(C=C6)Cl)F)=NC=C5)C(F)=C4)F)=N2)=CC(C(O)=O)=C1
Biological Activity
DescriptionGLP-1R Agonist 18 is a potent agonist for the glucagon-like peptide-1 receptor (GLP-1R), exhibiting an EC50 of 0.044 nM. This compound enhances insulin secretion in response to glucose, making it a valuable tool for research in diabetes and metabolic disorders. Its high affinity for GLP-1R positions it as a significant candidate for investigating therapeutic strategies targeting glucose homeostasis and appetite regulation.
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