Product Data Sheet

GLP-1R agonist 19

Catalog No. A60622

main product photo
GLP-1R agonist 19 is a potent and selective agonist of the glucagon-like peptide-1 receptor (GLP-1R). This compound demonstrates excellent plasma stability and liver microsomal stability, making it suitable for in vitro and in vivo studies. Additionally, it exhibits low hERG toxicity, ensuring a reduced risk of off-target effects. Research applications include investigations into glucose homeostasis, metabolic disorders, and potential therapeutics for type 2 diabetes.
Chemical Information
Catalog NumA60622
M. Wt1979.21
FormulaC94H136FN21O25
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2765065-09-4
Synonyms
SMILESNC([C@H](CCCC1=CC(C)=CC(C)=C1)NC([C@H](CC2=CC=C(C3=C(CC)C=C(OCCCCN4N=NC(COCCOCCOCCOCCOCCOCCOCCOCCN)=C4)C=C3)C=C2)NC([C@H](CC(O)=O)NC([C@H](CO)NC([C@H]([C@H](O)C)NC([C@@](CC5=C(F)C=CC=C5)(C)NC([C@H]([C@@H](C)O)NC(CNC([C@H](CC6=NNN=N6)NC(C(C)(C)C(NCCC7=CN=CN7)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Biological Activity
DescriptionGLP-1R agonist 19 is a potent and selective agonist of the glucagon-like peptide-1 receptor (GLP-1R). This compound demonstrates excellent plasma stability and liver microsomal stability, making it suitable for in vitro and in vivo studies. Additionally, it exhibits low hERG toxicity, ensuring a reduced risk of off-target effects. Research applications include investigations into glucose homeostasis, metabolic disorders, and potential therapeutics for type 2 diabetes.
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SHIPPING AND STORAGE
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