Product Data Sheet
JWU-A021
Catalog No. A60633
JWU-A021 is a GLP-1 secretagogue that functions by activating the TRPA1 cation channel, resulting in a calcium ion influx and increased intracellular calcium levels in enteroendocrine cells and TRPA1-transfected cells. This activation subsequently stimulates the secretion of glucagon-like peptide-1 (GLP-1) from intestinal enteroendocrine and L cells. JWU-A021 is valuable for research in the context of type 2 diabetes, offering insights into GLP-1 modulation and its potential therapeutic implications.
Chemical Information
| Catalog Num | A60633 |
|---|---|
| M. Wt | 257.76 |
| Formula | C16H16ClN |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1403610-23-0 |
| Synonyms | |
| SMILES | ClC1=CC2=C(NC3=C2C(C)(C4C=CC3C4)C)C=C1 |
Biological Activity
| Description | JWU-A021 is a GLP-1 secretagogue that functions by activating the TRPA1 cation channel, resulting in a calcium ion influx and increased intracellular calcium levels in enteroendocrine cells and TRPA1-transfected cells. This activation subsequently stimulates the secretion of glucagon-like peptide-1 (GLP-1) from intestinal enteroendocrine and L cells. JWU-A021 is valuable for research in the context of type 2 diabetes, offering insights into GLP-1 modulation and its potential therapeutic implications. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
