Product Data Sheet
Fsh receptor-binding inhibitor fragment(bi-10)
Catalog No. A60667
FSH receptor-binding inhibitor fragment (bi-10) is a specific antagonist of the follicle-stimulating hormone (FSH) receptor (FSHR). This compound effectively inhibits FSH from binding to its receptor, thereby modifying FSH activity at the receptor level. Research indicates that bi-10 can suppress ovulation and induce follicular atresia in murine models. Additionally, it may offer potential therapeutic strategies for mitigating ovarian cancer by downregulating the overexpression of FSHR and estrogen receptor beta (ERβ) in ovarian tissues.
Chemical Information
| Catalog Num | A60667 |
|---|---|
| M. Wt | 1058.06 |
| Formula | C42H67N13O19 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 163973-98-6 |
| Synonyms | |
| SMILES | C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@@H](C)O)N)=O)CCC(O)=O)=O)CC(N)=O)=O)CC(C)C)=O)CCC(O)=O)(=O)N1[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N)=O)=O)CCC(O)=O)=O)=O)CC(N)=O)=O)CCC1 |
Biological Activity
| Description | FSH receptor-binding inhibitor fragment (bi-10) is a specific antagonist of the follicle-stimulating hormone (FSH) receptor (FSHR). This compound effectively inhibits FSH from binding to its receptor, thereby modifying FSH activity at the receptor level. Research indicates that bi-10 can suppress ovulation and induce follicular atresia in murine models. Additionally, it may offer potential therapeutic strategies for mitigating ovarian cancer by downregulating the overexpression of FSHR and estrogen receptor beta (ERβ) in ovarian tissues. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
