Product Data Sheet
GnRH-R antagonist-3
Catalog No. A60668
GnRH-R antagonist-3 is a potent gonadotropin-releasing hormone receptor (GnRH-R) antagonist with IC50 values of 94 nM for rat GnRH-R and 275 nM for human GnRH-R. This compound demonstrates significant potential in the study of hormone-dependent diseases, including endometriosis, breast cancer, and prostate cancer. It serves as a valuable tool for researchers investigating the therapeutic mechanisms and biological pathways associated with these conditions.
Chemical Information
| Catalog Num | A60668 |
|---|---|
| M. Wt | 645.90 |
| Formula | C37H51N5O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 666852-12-6 |
| Synonyms | |
| SMILES | O=C(N1CCOCC1)NCC2CCN(CC2)CCC3=C(C4=CC(C)=CC(C)=C4)NC5=C3C=C(C(C)(C)C(N6C7CCC6CC7)=O)S5 |
Biological Activity
| Description | GnRH-R antagonist-3 is a potent gonadotropin-releasing hormone receptor (GnRH-R) antagonist with IC50 values of 94 nM for rat GnRH-R and 275 nM for human GnRH-R. This compound demonstrates significant potential in the study of hormone-dependent diseases, including endometriosis, breast cancer, and prostate cancer. It serves as a valuable tool for researchers investigating the therapeutic mechanisms and biological pathways associated with these conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
